George Clooney, Ashlee Simpson Late Show with David Letterman : Season 13 Episode 51
TV-PG CBS 1h 00m int(0)
Aired: November 21st, 2005 @ 7:00 PM EST on CBS
Dave shocks the audience with the news that Oprah Winfrey will be a guest on the show a week from Thursday; Biff undergoes Lasek eye surgery; George Clooney promotes "Syriana."